In the context of acidosis, when the gut wall becomes more permeable, LPS can cross from the rumen into the lumen of the gut. Photo: Herbert Wiggerman
We are all well versed in understanding acidosis, but do we truly understand the cost of a leaky gut? What was once a topic of pH has now transitioned into the wider impacts of microbiology, endocrinology, physiology and immunology. Here we will consider the connection between acidosis, leaky gut, and the challenge of endotoxins, particularly lipopolysaccharides (LPS), being absorbed through the gut wall, causing an inflammatory response. We will also consider the mechanisms behind this infla
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